Alces Bioworks
Alces Bioworks uses revolutionary protein design technologies to create superior affinity reagents for its customers.
We call these affinity reagents Alceins™
Alceins™ are used like monoclonal antibodies, but they have several advantages
- Designed, so you know precisely how they bind to your target
- Fast, delivered in weeks instead of months for a monoclonal antibody
Modular, so they can be attached to various reporter tags
Easy to make and highly stable
Humane, because animals are not used to make Alceins™
What do we mean by affinity reagents?
Technology – what is an Alcein™
- An Alcein™ is an affinity reagent designed and made by Alces Bioworks.
- We created a computational pipeline that efficiently designs small proteins (Alceins™) to bind your target protein of interest.
- We can specify where on your target protein the Alcein™ should bind.
- Alceins™ are made in E. coli, so they can be produced quickly and in high yields.
- Designed proteins such as Alceins™ tend to be very stable.
FAQ
Why are Alceins™ better than antibodies?
Alceins™ are custom-designed affinity reagents that offer a powerful alternative to traditional antibodies, with key advantages for researchers and biotech professionals:
- Designed in silico using advanced computational protein design, ensuring high specificity and performance.
- Produced in E. coli, enabling rapid, scalable, and cost-effective recombinant protein production.
- Structurally defined—our engineered proteins have known molecular structures because we designed them.
- Modular format—customizable with detection tags such as GFP, GST, His-tag, biotin, and others to meet your application needs.
- Animal-friendly—no animals are used at any stage. We don’t need to immunize mice, rabbits, alpacas, not even moose!
Instead of an affinity reagent, could you develop an Alcein™ drug or diagnostic for my organization?
While our core mission is to deliver high-quality reagents quickly and efficiently, we welcome opportunities for research collaborations. If you’re interested in developing a custom Alcein™ for a diagnostic or therapeutic application, contact us to start the conversation.
How do you design Alceins™?
At Alces Bioworks, we focus on advancing protein design technology, so you can focus on your science. The field is evolving rapidly, with new computational design tools emerging in the literature almost daily, and we move just as quickly to adapt accordingly.
Our team thrives on exploring the latest in protein engineering and machine learning: from message-passing neural networks, iPTM, AlphaFold, pLDDT, PAE, Boltz, diffusion, backpropagation, biolayer interferometry, and surface plasmon resonance.
Our mission is simple: to deliver high-performance affinity reagents—fast, precisely designed, and ready to accelerate your research.
How do I place an order?
Placing an order is simple. Just submit your contact information through our Contact Us page, and we’ll send you a personalized link to our order form. Once we receive your request, we’ll provide a quote and agree on the payment method.
It’s a quick, streamlined process, so you can get your custom Alcein™ project started without delay.